Responding well to exercise is dependent on a number of factors - one of which is genes. A New York Times blog post (link below) describes a relatively new way individuals can find out whether they will be successful achieving positive health outcomes through exercise. In my opinion, the test should be taken only after an exercise and diet regimen has been tried first.
Link: http://well.blogs.nytimes.com/2012/10/10/are-you-likely-to-respond-to-exercise/
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